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Št. zadetkov: 8
The role of irradiation induced changes in tumor vasculature on the infiltration of immune cells in colon cancer
Iva Šantek, Gregor Serša, Boštjan Markelc
Raziskovalni podatki
Oznake: colon cancer;radiotherapy;tumor microenvironment;endothelial cells;endothelial activation;tumor vasculature;
Colon cancer is the second most prevalent cancer in women and the third in men. The conventional therapies for treating colon cancer include surgery, chemotherapy, and radiotherapy (RT); however, they are often ineffective. The main mode of action of RT is the killing of proliferating cancer cells b ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
The role of irradiation induced changes in tumor vasculature on the infiltration of immune cells in colon cancer​​
Iva Šantek, Gregor Serša, Boštjan Markelc
Doktorska disertacija
Oznake: Radiotherapy;Irradiation;Tumor vasculature;Colon cancer;Endothelial cells;Endothelial activation;Tumor microenvironment;Immune response;
Scientific background: Colon cancer is the second most prevalent cancer in women and the third in men. The conventional therapies for treating colon cancer include surgery, chemotherapy, and radiotherapy (RT); however, they are often ineffective. The main mode of action of RT is the killing of proli ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Molekularne in transkripcijske spremembe tumorskih endotelijskih celic po obsevanju pri miših
Iva Šantek, Tim Božič, Gregor Serša, Boštjan Markelc
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: miši;obsevanje;gensko zdravljenje;
Leto: 2023 Vir: Onkološki inštitut Ljubljana (OI)
Vpliv radioterapije na aktivacijo tumorskih endotelijskih celic
Iva Šantek, Tim Božič, Gregor Serša, Boštjan Markelc
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: radioterapija;patologija;onkologija;
Leto: 2024 Vir: Onkološki inštitut Ljubljana (OI)
Spremembe tumorskega žilja po radioterapiji
Iva Šantek, Tim Božič, Gregor Serša, Boštjan Markelc
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: eksperimentalna onkologija;radioterapija;elektrokemoterapija;
Leto: 2025 Vir: Onkološki inštitut Ljubljana (OI)
Characterization of two distinct immortalized endothelial cell lines, EA.hy926 and HMEC-1, for in vitro studies
Barbara Starešinič, Tim Božič, Iva Šantek, Boštjan Markelc, Milka Vrecl, Robert Frangež, Maja Čemažar
Izvirni znanstveni članek
Oznake: endothelial cells;calcium electroporation;calcium kinetics;transcriptomic profiling;
Background Disruption of Ca2+ homeostasis after calcium electroporation (CaEP) in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on healthy tissue, such as endothelium. Therefore, our study aimed to determine differences in Ca2+ kinetics and gene expression involve ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Chemokine CCL5 overexpression combined with radiotherapy modulates Th1-mediated immune response and leads to significant tumor growth delay in mouse tumor models
Tim Božič, Iva Šantek, Živa Modic, Simona Kranjc, Gregor Serša, Boštjan Markelc, Maja Čemažar
Izvirni znanstveni članek
Oznake: cemokini;elektroprenos genov;gensko zdravljenje;miši;radioterapija;chemokines;gene electrotransfer;gene therapy;mouse;radiotherapy;
This study investigated the antitumor efficacy of chemokine CCL5 gene therapy using gene electrotransfer (GET) in combination with radiotherapy (RT) in solid murine tumors CT26 and 4T1. In vitro, CT26 and 4T1 tumor cells transfected with plasmid DNA (pDNA) encoding CCL5 induced migration of RAW264.7 ...
Leto: 2026 Vir: Onkološki inštitut Ljubljana (OI)
Učinki obsevanja mišjih tumorjev na naučeno imunost in naravne celice ubijalke
Tim Božič, Boštjan Markelc, Barbara Starešinič, Iva Šantek, Simona Kranjc, Živa Modic, Tanja Dolinšek, Maja Čemažar
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: eksperimentalna onkologija;miši;celice ubijalke;
Leto: 2025 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 8
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