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The role of tricyclic drugs in selective triggering of mitochondrially-mediated apoptosis in neoplastic glia: a therapeutic option inmalignant glioma?
Geoffrey J. Pilkington, James Akinwunmi, Sabina Amar
Pregledni znanstveni članek
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We have previously demonstrated that the tricyclic antidepressant, Clomipramine, exerts a concentration - dependent, tumor cell specific, pro-apoptotic effect on human glioma cells in vitro and than this effect is not mirrored in non-neoplastic human astrocytes. Moreover, the drug acts by triggering ...
Leto: 2006 Vir: dLib.si Digitalna knjižnica Slovenije
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