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Št. zadetkov: 5
Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment
Jiewen Wang, Guangbo Kang, Haibin Yuan, Xiaocang Cao, He Huang, Ario De Marco
Pregledni znanstveni članek
Oznake: nanobody multimers;immunomodulation;intrabodies;imaging;nanobody functionalization;
Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Novel bispecific nanobody mitigates experimental intestinal inflammation in mice by targeting TNF-[alpha] and IL-23p19 bioactivities
Jiewen Wang, Guangbo Kang, Huiying Lu, Ario De Marco, Haibin Yuan, Zelin Feng, Mengxue Gao, Xiaoli Wang, Huahong Wang, Xiaolan Zhang
Izvirni znanstveni članek
Oznake: bispecific constructs;nanobodies;intestinal inflammation;
Leto: 2024 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Affinity maturation of antibody fragments
Jiaqi Liu, Guangbo Kang, Jiewen Wang, Haibin Yuan, Yili Wu, Shuxian Meng, Ping Wang, Miao Zhang, Yuli Wang, Yuanhang Feng, He Huang, Ario De Marco
Pregledni znanstveni članek
Oznake: deep learning;protein modeling;random mutagenesis;rational mutagenesis;
Affinity maturation of antibody fragments
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Effect of humanizing mutations on the stability of the llama single-domain variable region
Miguel A. Soler, Barbara Medagli, Jiewen Wang, Sandra Oloketuyi, Gregor Bajc, He Huang, Sara Fortuna, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobody framework;modeling;nanobody humanization;CDR grafting;
Effect of humanizing mutations on the stability of the llama single-domain variable region
Leto: 2021 Vir: Biotehniška fakulteta (UL BF)
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Zixuan Bai, Jiewen Wang, Jiaqi Liu, Haibin Yuan, Ping Wang, Miao Zhang, Yuanhang Feng, Xiangtong Cao, Xiangan Cao, Guangbo Kang, Ario De Marco, He Huang
Izvirni znanstveni članek
Oznake: nanobody rational design;bispecific binders;protein activity inhibition;
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 5
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