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ǂThe ǂconserved arginine cluster in the insert of the third cytoplasmic loop of the long form of the D2 dopamine receptor (D2L-R) acts as an intracellular retention signal
Valentina Kubale, Kaja Blagotinšek Cokan, Jane N. Larsen, Karin A Eidne, Milka Vrecl
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Oznake: D$_2$ dopamine receptors;endoplasmic reticulum (ER) retention motif;confocal microscopy;surface expression;bioluminescence resonance energy transfer (BRET$^2$);cAMP signaling;molecular biology;energy transfer techniques;metabolism;
This study examined whether the conserved arginine cluster present within the 29-amino acid insert of the long form of the D$_2$ dopamine receptor (D$_{2L}$-R) confers its predominant intracellular localization. We hypothesized that the conserved arginine cluster (RRR) located within the insert coul ...
Leto: 2016 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 1
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