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Št. zadetkov: 2
Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci
Karin Fransen, Mitja Mitrovič, Uroš Potočnik
Izvirni znanstveni članek
Oznake: inflammatory bowel diseases;IBD;genetic locus;genetics;
Background Genome-wide association studies of two main forms of inflammatory bowel diseases (IBD), Crohnʼs disease (CD) and ulcerative colitis (UC), have identified 99 susceptibility loci, but these explain only ~23% of the genetic risk. Part of the Žhidden heritabilityʼ could be in transmissible ge ...
Leto: 2012 Vir: Medicinska fakulteta (UM MF)
ǂThe ǂquest for genetic risk factors for Crohn's disease in the post-GWAS era
Karin Fransen, Mitja Mitrovič, Cleo C van Diemen, Rinse K. Weersma
Pregledni znanstveni članek
Oznake: genetic risk factors;Crohn’s disease;
Multiple genome-wide association studies (GWASs) and two large scale meta-analyses have been performed for Crohn's disease and have identified 71 susceptibility loci. These findings have contributed greatly to our current understanding of the disease pathogenesis. Yet, these loci only explain approx ...
Leto: 2011 Vir: Medicinska fakulteta (UM MF)
Št. zadetkov: 2
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