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Št. zadetkov: 4
Magistrsko delo
Oznake: fibroza;fibroblasti;pljučno tkivo;imunski sistem;epigenetika;
Izhodišča: Sistemska skleroza (SSc) je kronična sistemska avtoimunska bolezen vezivnega tkiva. Patogeneza bolezni še ni popolnoma poznana. Pogost vzrok smrti pri bolnikih s SSc je intersticijska pljučna bolezen. Naš namen je bil z uporabo javno dostopnih podatkovnih baz in bioinformatičnih orodij ug ...
Leto: 2019 Vir: Fakulteta za zdravstvene vede (UM FZV)
Izvirni znanstveni članek
Oznake: antineutrophil cytoplasmic antibodies (ANCA);proteinase 3 (PR3);myeloperoxidase (MPO);ANCA-associated vasculitis (AAV);chemiluminescent immunoassay;likelihood ratios (LRs);
Objectives: Antineutrophil cytoplasmic antibody (ANCA) testing assists clinicians diagnose ANCA-associated vasculitis (AAV). We aimed to verify and harmonize chemiluminescent immunoassays for the detection of myeloperoxidase (MPO)- and proteinase 3 (PR3)-ANCA. Methods: An in-house ELISA, a capture E ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake: cryoglobulins;cryoglobulinemic vasculitis;rheumatoid factor activity;complement components;cryoglobulin detection;pre-analytical phase;
The detection of cryoglobulins (CG) used to diagnose cryoglobulemic vasculitis requires strict adherence to protocol, with emphasis on the preanalytical part. Our main objectives were to introduce a more sensitive and specific protocol for the detection of CG and to characterize CG in Slovenian pati ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake: mesenchymal stem cells;nephrotoxicity;
Mesenchymal stem cells (MSCs) are recognised as a promising tool to improve renal recovery in experimental models of cisplatin-induced acute kidney injury. However, these preclinical studies were performed on severely immunodeficient animals. Here, we investigated whether human umbilical cord derive ...
Leto: 2016 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 4
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