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Št. zadetkov: 13
ǂA ǂsingle-cell functional precision medicine landscape of multiple myeloma
Klara Kropivšek
Prispevek na konferenci brez natisa
Oznake:
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Machine learning-guided nanobody discovery for enhanced biomarker research
Klara Kropivšek
Prispevek na konferenci brez natisa
Oznake:
Leto: 2024 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂsingle-cell functional precision medicine landscape of multiple myeloma
Klara Kropivšek
Doktorska disertacija
Oznake: multiple myeloma;personalized medicine;high-throughput confocal microscopy;proteotyping;observational clinical trial;pharmacoscopy;Hematologic neoplasms;plasma cell;deep learning;doctoral thesis;
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂroadmap of therapeutic strategies for patients with multiple myeloma
Berend Snijder, Klara Kropivšek
Kratki znanstveni prispevek
Oznake: multiple myeloma;multiomics;deep learning;imaging;ex vivo drug screening;
Multiple myeloma is a rare and incurable cancer of plasma cells. To characterize this cancer, we developed an ex vivo drug screening method that combines imaging, deep learning and multiomics and applied it in an observational trial, uncovering new potential therapeutic strategies and underlying dis ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
From concept to HPC computing
Žiga Zebec, Samo Miklavc, Klara Kropivšek
Radijska ali televizijska oddaja
Oznake: EuroHPC;computational resources;protein;antigens;antibody;AlphaFold3;Chai-1;Boltz2;accuracy;efficiency;Epicure;VEGA;
This presentation will dive into computational resources available to users on the national level via SLING or from EuroHPC JU, highlighting both advantages and limitations. The challenges faced by our users will be illustrated through a real-life example presented by Klara Kropivšek, who leverages ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Postnatal dynamics of Zeb2 expression in rat brain
Klara Kropivšek, Jasmine Pickford, David A. Carter
Izvirni znanstveni članek
Oznake: transcription factor;RNA;untranslated region;miRNA;brain;rat;
ZEB2 is a transcription factor with established roles in neurogenesis but no defined function in postnatal brain despite extensive neuronal expression in telencephalic structures. Multiple, incompletely annotated transcripts derive from the Zeb2 locus; the purpose of the present study was to structu ...
Leto: 2014 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
NatiNb: a naïve llama nanobody database
Klara Kropivšek, Gemma Gordon, Katharina Dost, Charlotte Deane, Ario De Marco
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: nanobody;binders;naive library;database;sequencing;
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Weak evidence for heritable changes in response to selection by aphids in Arabidopsis accessions
Marc W. Schmid, Klara Kropivšek, Samuel E. Wuest, Bernhard Schmid, Ueli Grossniklaus
Drugi članki ali sestavki
Oznake: epigenetic variation;genetic variation;transgenerational inheritance;epialleles;arabidopsis thaliana;herbivory;selection experiment;maternal effects;bolting time;
Abstract In plants, transgenerational inheritance of certain epialleles has been observed but experimental evidence for selection of epigenetic variation independent of genetic variation is scarce. We extended an experiment simulating selection in response to herbivory inArabidopsis thalianato as ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Weak evidence for heritable changes in response to selection by aphids in Arabidopsis accessions
Marc W. Schmid, Klara Kropivšek, Samuel E. Wuest, Bernhard Schmid, Ueli Grossniklaus
Izvirni znanstveni članek
Oznake: Arabidopsis thaliana;epigenetic variation;DNA methylation;selection;aphids;transgenerational inheritance;
In plants, transgenerational inheritance of certain epialleles has been observed but experimental evidence for selection of epigenetic variation independent of genetic variation is scarce. We extended an experiment simulating selection in response to herbivory in Arabidopsis thaliana to assess a pot ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂnovel dual-cytokine-antibody fusion protein for the treatment of CD38-positive malignancies
Roberto De Luca, Paul Kachel, Klara Kropivšek, Berend Snijder, Markus G. Manz, Dario Neri
Izvirni znanstveni članek
Oznake: antibodies;dual-cytokine-antibody;CD38;multiple myeloma;TRAIL, IL2;
A novel dual-cytokine–antibody fusion protein, consisting of an antibody directed against CD38 [a tumor-associated antigen mainly expressed on the surface of multiple myeloma (MM) cells], simultaneously fused to both tumor necrosis factor ligand superfamily member 10 (TRAIL) and interleukin-2 (IL2), ...
Leto: 2018 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 13
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