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APS8, a polymeric alkylpyridinium salt blocks [alpha]7 nAChR and induces apoptosis in non-small cell lung carcinoma
Ana Zovko, Kristina Viktorsson, Rolf Lewensohn, Katja Kološa, Metka Filipič, Hong Xing, William R. Kem, Laura Paleari, Tom Turk
Izvirni znanstveni članek
Oznake: 3-alkylpyridinium polymers;apoptosis;nicotine;nicotinic acetylcholine receptor;non-small cell lung carcinoma;
Naturally occurring 3-alkylpyridinium polymers (poly-APS) from the marine sponge Reniera sarai, consisting of monomers containing polar pyridinium and nonpolar alkyl chain moieties, have been demonstrated to exert a wide range of biological activities, including a selective cytotoxicity against non- ...
Leto: 2013 Vir: Nacionalni inštitut za biologijo (NIB)
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