Št. zadetkov: 9
Doktorska disertacija
Oznake:
streptokoki skupine B;makrofagi;fagocitoza;imunometabolizem;citokini;piroptoza;imunski odziv;
Streptokoki skupine B (GBS) ostajajo vodilni vzrok invazivnih neonatalnih okužb, ki se običajno kažejo kot sepsa, meningitis ali pljučnica. Do danes je opisanih 10 različnih serotipov (Ia, Ib, II – IX), ki se razlikujejo po svoji virulenci in imunskem odzivu, ki ga sprožijo. Ker ob porodna antibioti ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
chronic inflammation;complement system;inflammasomes;innate immunity;NLRP3;
Chronic inflammation underlies a broad range of human diseases, including autoimmune disorders, neurodegeneration, and metabolic syndromes. While acute inflammation is essential for pathogen clearance and tissue repair, persistent activation leads to tissue damage and disease progression. Two key in ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
elektrokemoterapija;rak dojke;olaparib;bleomycin;electrochemotherapy;breast cancer;
Electrochemotherapy (ECT), a local therapy, has different effectiveness among tumor types. In breast can-cer, its effectiveness is low; therefore, combined therapies are needed. The aim of our study was to com-bine ECT with PARP inhibitor olaparib, which could inhibit the repair of bleomycin or cisp ...
Leto:
2021
Vir:
Onkološki inštitut Ljubljana (OI)
Izvirni znanstveni članek
Oznake:
nanodelci PdC;izpostavljene rastline;razvoj kalic;
Namen: ugotoviti vpliv dveh koncentracij nanodelcev paladija (nano PdC), na razvoj kalic sončnice (Helianthus annuus) in ječmena (Hordeum vulgare L.).
Metode: kalitev semen sončnice in ječmena, spremljanje rasti in razvoja kalic v treh skupinah, meritev rastnih parametrov (dolžina poganjka in najda ...
Leto:
2018
Vir:
Biotehniška fakulteta (UL BF)
Magistrsko delo
Oznake:
elektrokemoterapija;citostatiki;olaparib;citotoksičnost;
Elektrokemoterapija je kombinirana fizikalno-kemijska metoda, pri kateri z izpostavitvijo celic ali tkiva električnim pulzom povzročimo privzem citostatikov v celico. Je lokalna metoda zdravljenja z malo neželenimi učinki in nizko toksičnostjo. Kot najprimernejši zdravili sta se do sedaj izkazala bl ...
Leto:
2019
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Izvirni znanstveni članek
Oznake:
clinical isolate heterogeneity;Group B Streptococcus;immune evasion;inflammation;macrophages;preterm birth;pyroptosis;
Background: Group B Streptococcus (GBS) remains a leading cause of neonatal sepsis and meningitis despite preventive strategies. Disease severity and clinical presentation vary widely and are influenced by strain-specific virulence traits. Macrophages are key innate immune sentinels during GBS infec ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
MIS-C;biomarkerji;metabolizem;B limfociti;T limfociti;monociti;aktivacija limfocitov;dendritske celice;biomarkers;metabolism;B lymphocytes;T lymphocytes;monocytes;lymphocyte activation;dendritic cells;
Alterations in immunophenotype and metabolic profile of mononuclear cells during follow up in children with multisystem inflammatory syndrome (MIS-C)
Leto:
2023
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Lucija Levstek,
Irena Auersperger,
Larisa Janžič,
Andreja Nataša Kopitar,
Katarina Reberšek,
Barbara Jezeršek Novaković,
Polona Novak,
Karla Rener,
Klara Šlajpah,
Alojz Ihan,
Samo Zver,
Matjaž Sever
Izvirni znanstveni članek
Oznake:
celično zdravljenje CAR T;neželeni učinki;difuzni velikocelični limfom;krvni raki;CAR T cell therapy;adverse events;diffuse large B-cell lymphoma;hematologic malignancies;
CAR T cell therapy is a promising immunotherapy for hematologic malignancies, yet early prediction of outcomes and adverse events remains difficult, especially in small real-world cohorts. We retrospectively analyzed 14 adult patients with diffuse large B-cell lymphoma (DLBCL) treated with CAR T cel ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Maša Bizjak,
Maša Bizjak,
Jakob Peterlin,
Tadej Avčin,
Miroslav Petrovec,
Alojz Ihan,
Mojca Zajc Avramovič,
Gašper Markelj,
Tina Vesel,
Veronika Osterman,
Jerneja Ahčan,
Helena Mole,
Katja Dejak Gornik,
Alenka Biteznik,
Sara Jevnikar,
Larisa Janžič,
Miha Bajc,
Andreja Nataša Kopitar,
Nataša Toplak
Izvirni znanstveni članek
Oznake:
varicella vaccination;juvenile idiopathic arthritis;biologic therapy;anti-cytokine therapy;
Objective: To evaluate safety, long-term effectiveness and immunogenicity of varicella vaccination in children with JIA, treated with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods: This is a prospective case-control study. VZV-naive patients with JIA on selected bDMARDs (TNFi, IL ...
Leto:
2025
Vir:
Repozitorij Univerze v Ljubljani (RUL)