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Št. zadetkov: 4
Oleinska kislina
Lena Trnovec, Ksenija Kogej
Diplomsko delo
Oznake: oleinska kislina;vezikli;kritična micelna koncentracija;potenciometrična titracija;diplomska dela;
Oleinska kislina s formulo C18H34O2H sodi med omega-9 maščobne kisline. Med naravnimi maščobnimi kislinami je najbolj razširjena. Sodeluje pri proizvodnji celične energije in drugih metabolnih funkcijah, zato je bistvena za človeško telo. Zelo pomembna je v prehrani, saj jo povezujejo z zmanjševanje ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Actionable gene expression cell profiling with foundation models
Lena Trnovec, Blaž Zupan, Gad Shaulsky
Magistrsko delo
Oznake: foundation models;cell embeddings;single-cell analysis;transfer learning;computer science;master's thesis;
Modern techniques for analyzing cellular data enable a deeper understanding of diseases and the development of more effective therapies. Recently, foundation models — advanced neural networks trained on vast amounts of data — have been developed, representing an important advancement in the analysis ...
Leto: 2025 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development
Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Blaž Zupan, Gad Shaulsky
Izvirni znanstveni članek
Oznake: genska pot zelene brade;medsebojna genska inhibicija;analiza transkriptomskih podatkov;greenbeard pathway;mutual suppression;transcriptome data analysis;
Background The Dictyostelium greenbeard pathway is mediated by two polymorphic transmembrane proteins,the TgrC1 ligand and the TgrB1 receptor. These proteins mediate allorecognition, altruism, and the developmental transition to multicellularity. A genetic suppressor screen revealed activating mut ...
Leto: 2025 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Early cAMP signaling orchestrates single-cell synchronicity throughout Dictyostelium development
Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Rui Chen, Yumei Li, Blaž Zupan, Gad Shaulsky
Izvirni znanstveni članek
Oznake: cAMP signalizacija;Dictyostelium discoideum;sinhronost celic;razvoj;transkriptomika;cAMP;cell synchronicity;development;transcriptomics;
Synchronicity is observed in many biological systems, including development, as seen in vertebrate body axis formation, fly eye development, and development of the social amoeba D. discoideum. Despite its prevalence, quantitative analyses of synchronicity at the single-cell level remain rare. Here w ...
Leto: 2026 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Št. zadetkov: 4
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