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Immobilized and recyclable catalysts for deuterium labelling
Liju Raju, Luka Jedlovčnik, Janez Košmrlj, Ross D. Jansen-van Vuuren
Pregledni znanstveni članek
Oznake: imobiliziran;primeren za recikliranje;katalizator;deuteriranje;kemija s kontinuiranim pretokom;izotopska izmenjava;označevanje z devterijem;nosilec;immobilized;suitable for recycling;catalyst;deuteration;continuous-flow chemistry;isotope exchange;deuterium labeling;carrier;
Deuterated compounds have become indispensable across a wide range of applications in medicinal chemistry and materials science, driving interest in the development of efficient and sustainable synthetic methodologies. In particular, there is a growing emphasis on greener approaches that enable deut ...
Leto: 2026 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Deuteration of six-membered N-heteroarenes
Liju Raju, Davide Benedetto Tiz, Adrian Iles, Janez Košmrlj, Ross D. Jansen-van Vuuren
Pregledni znanstveni članek
Oznake: deuteriranje;devterij;označevanje z devterijem;označevanje z izotopi;N-heteroaren;N-heteroaromatski;piridin;pirimidin;pirazin;piridazin;kinolin;kinazolin;elektronsko pomanjkljiv;triazin;tetrazin;organska elektronika;farmacevtski izdelki;barvila;deuteration;deuterium;deuterium-labelling;isotope-labelling;N-heteroarene;N-heteroaromatic;pyridine;pyrimidine;pyrazine;pyridazine;quinoline;quinazoline;electron-deficient;triazine;tetrazine;organic electronics;pharmaceuticals;dyes;
Six-membered N-heteroarenes (“6NHetAr”) play pivotal roles in the pharmaceutical, agrochemical, and materials science industries. In recent times, deuterium (D)-labelled 6NHetAr have demonstrated enhanced performance over their unlabelled counterparts. For example, VV116 and VX-984, approved therape ...
Leto: 2025 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
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