Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 1
Structural aspects of Mycobacterium tuberculosis DNA gyrase targeted by novel bacterial topoisomerase inhibitors
Maja Kokot, Martina Hrast, Lipeng Feng, Lesley A Mitchenall, David M. Lawson, Anthony Maxwell, Tanya Parish, Nikola Minovski, Marko Anderluh
Izvirni znanstveni članek
Oznake: DNA giraza;Mycobacterium tuberculosis;inhibitorji;bakterijske topoizomeraze;NBTIs;DNA gyrase;M. tuberculosis;crystal structure;bifurcated halogen bonds;
In this Letter, we present a small series of novel bacterial topoisomerase inhibitors (NTBIs) that exhibit both potent inhibition of Mycobacterium tuberculosis DNA gyrase and potent antimycobacterial activity. The disclosed crystal structure of M. tuberculosis DNA gyrase in complex with DNA and comp ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 1
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: