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Št. zadetkov: 7
Clinical significance of histologic subtyping of malignant pleural mesothelioma
Luka Brčić, Izidor Kern
Pregledni znanstveni članek
Oznake: maligni mezoteliom;epiteloidni maligni mezoteliom;bifazni maligni mezoteliom;sarkomatoidni maligni mezoteliom;malignant mesothelioma;epithelioid malignant mesothelioma;biphasic malignant mesothelioma;sarcomatoid malignant mesothelioma;
Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best progno ...
Leto: 2020 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Outsourcing predictive biomarker testing in non-small cell carcinoma
Luka Brčić, Izidor Kern
Kratki znanstveni prispevek
Oznake: non-small cell lung carcinoma;diagnostic pathology;predictive biomarkers;
Outsourcing predictive biomarker testing in non-small cell carcinoma : a personal view of pathologists
Leto: 2020 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Reproducibility of malignant pleural mesothelioma histopathologic subtyping
Luka Brčić, Gregor Vlačić, Franz Quehenberger, Izidor Kern
Izvirni znanstveni članek
Oznake: malignant pleural mesothelioma;histopathology;
Context. Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis. Several studies have analyzed potential prognostic markers, but histologic type remains the single most important prognostic factor. Histologic subtypes of epithelioid MPM seem to have prognostic and therapeutic impli ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
NSCLC molecular testing in Central and Eastern European countries
Ales Ryška, Peter Berzinec, Luka Brčić, Tanja Čufer, Rafal Dziadziuszko, Maya Gottfried, Ilona Kovalszky, Włodzimierz Olszewski, Buge Oz, Lukas Plank, József Tímár
Izvirni znanstveni članek
Oznake: EGFR mutations;ALK rearrangements;Central Europe;Eastern Europe;Srednja Evropa;Vzhodna Evropa;
Background: The introduction of targeted treatments for subsets of non-small cell lung cancer (NSCLC) has highlighted the importance of accurate molecular diagnosis to determine if an actionable genetic alteration is present. Few data are available for Central and Eastern Europe (CEE) on mutation ra ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Prognostic impact of PD-1 and PD-L1 expression in malignant pleural mesothelioma
Luka Brčić, Thomas Klikovits, Zsolt Megyesfalvi, Berta Mosleh, Katharina Sinn, Richard Hritcu, Viktoria Laszlo, Tanja Čufer, Aleš Rozman, Izidor Kern, Katja Mohorčič
Izvirni znanstveni članek
Oznake: maligni plevralni mezoteliom;ligand programirane celične smrti 1;programirana celična smrt 1;PD-L1;malignant pleural mesothelioma;programmed death-ligand 1;programmed cell death 1;
Background: Programmed cell death 1/programmed death ligand 1 (PD-1/PD-L1) immune-checkpoint blockade is a promising new therapeutic strategy in cancer. However, expression patterns and prognostic significance of PD-L1 and PD-1 are still controversial in human malignant pleural mesothelioma (MPM). M ...
Leto: 2021 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Lung cancer biomarker testing
Erik Thunnissen, Birgit Weynand, Dalma Udovicic-Gagula, Luka Brčić, Malgorzata Szolkowska, Paul Hofman, Silvana Smojver-Ježek, Sisko Anttila, Fiorella Calabrese, Izidor Kern
Pregledni znanstveni članek
Oznake: pljučni rak;napovedno testiranje;lung cancer;predictive testing;
A questionnaire on biomarker testing previously used in central European countries was extended and distributed in Western and Central European countries to the pathologists participating at the Pulmonary Pathology Society meeting 26-28 June 2019 in Dubrovnik, Croatia. Each country was represented b ...
Leto: 2020 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Non-small cell lung cancer in countries of Central and Southeastern Europe
Ales Ryška, Rares Buiga, Albena Fakirova, Izidor Kern, Włodzimierz Olszewski, Lukas Plank, Sven Seiwerth, Erika Toth, Eri Zivka, Christiane Thallinger, Christoph Zielinski, Luka Brčić
Izvirni znanstveni članek
Oznake: Central Europe;Southeastern Europe;reimbursement;
This article analyzes the availability of different diagnostic procedures of non-small cell lung cancer (NSCLC) and the reimbursement landscape of drugs for NSCLC in countries of central and southeastern Europe (CEE). A survey was conducted by the Central European Cooperative Oncology Group. Results ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 7
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