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Št. zadetkov: 8
Povezava kazalnikov oksidativnega stresa z aktivnostjo kronične vnetne črevesne bolezni pri zdravljenju z ustekinumabom
Manca Kralj, Tomaž Vovk, Armando Tratenšek
Magistrsko delo
Oznake: kronična vnetna črevesna bolezen;Crohnova bolezen;ulcerozni kolitis;kazalniki oksidativnega stresa;ustekinumab;
Incidenca in prevalenca kronične vnetne črevesne bolezni rasteta. Diagnoza bolezni je pogosto zakasnjena, saj so simptomi nespecifični, s tem pa je povezana slabša kakovost življenja bolnikov in večja možnost zapletov. Trenutno uporabljene diagnostične metode so invazivne in drage, s čimer narašča p ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Vpliv nanomateriala črnega ogljika na membrane krvnih celic
Manca Pajnič, Veronika Kralj-Iglič, Andrej Starc
Doktorska disertacija
Oznake: črni ogljik;nanomaterial;krvne celice;oblika eritrocitov;diskociti;stomatociti;ehinociti;trombociti;levkociti;orjaški unilamelarni fosfolipidni mehurčki;disertacije;
V doktorskem delu smo proučevali vpliv nanomateriala črnega ogljika (NM CB) na membrane krvnih celic ter orjaške unilamelarne fosfolipidne mehurčke (OUFM). Glavni namen je bilo ugotoviti, ali dodani NM CB vpliva na biološke membrane, tako plazemske celične membrane kot tudi membrane OUFM. Izolirane ...
Leto: 2019 Vir: Zdravstvena fakulteta (UL ZF)
Applicability of platelet- and extracellular vesicle-rich plasma in medicine
Domen Vozel, Marko Jeran, Darja Božič, Ljubiša Pađen, Manca Pajnič, Bojana Uršič, Veronika Kralj-Iglič, Saba Battelino
Objavljeni znanstveni prispevek na konferenci (vabljeno predavanje)
Oznake: platelets;platelet-rich plasma;extracellular vesicles;regenerative effects;haemostasis;immune response;blood immune cells;
Platelet-rich plasma is a blood-derived product with proven favourable effects after a local application in various healing disorders. It is also rich with extracellular vesicles - a heterogeneous group of nano- to micro-sized membranous structures -that are considered as the main mediators of regen ...
Leto: 2019 Vir: Zdravstvena fakulteta (UL ZF)
Viscosity of plasma as a key factor in assessment of extracellular vesicles by light scattering
Darja Božič, Simona Prelesnik, Ita Junkar, Roman Štukelj, Manca Pajnič, Ema Žagar, Veronika Kralj-Iglič, Ksenija Kogej
Izvirni znanstveni članek
Oznake: izvencelični vezikli;eksosomi;krvna plazma;dinamično sipanje svetlobe;statično sipanje svetlobe;določanje oblike;viskoznost krvne plazme;extracellular vesicles;exosomes;blood plasma;dynamic light scattering;static light scattering;shape characterization;viscosity of blood plasma;
Extracellular vesicles (EVs) isolated from biological samples are a promising material for use in medicine and technology. However, the assessment methods that would yield repeatable concentrations, sizes and compositions of the harvested material are missing. A plausible model for the description o ...
Leto: 2019 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling
Darja Božič, Domen Vozel, Matej Hočevar, Marko Jeran, Zala Jan, Manca Pajnič, Ljubiša Pađen, Aleš Iglič, Saba Battelino, Veronika Kralj-Iglič
Izvirni znanstveni članek
Oznake: cellular vesicles;extracellular vesicles;microvesicles;platelet microparticles;platelet rich plasma;wound healing;
In order to prepare optimal platelet and extracellular vesicle (EV)-rich plasma for the treatment of chronic temporal bone inflammation, we studied effects of centrifugation parameters on redistribution of blood constituents in blood samples of 23 patients and 20 volunteers with no record of disease ...
Leto: 2022 Vir: Fakulteta za elektrotehniko (UL FE)
Decrease in cellular nanovesicles concentration in blood of athletes more than 15 hours after marathon
Zala Jan, Mitja Drab, Damjana Drobne, Apolonija Bedina Zavec, Mojca Benčina, Barbara Drašler, Matej Hočevar, Judita Lea Krek, Ljubiša Pađen, Manca Pajnič, Neža Repar, Boštjan Šimunič, Roman Štukelj, Veronika Kralj-Iglič, Veronika Kralj-Iglič
Izvirni znanstveni članek
Oznake: membrane vesiculation;physical effort;blood samples;inflammation process;cellular nanovesicles;marathon;
Introduction: Cellular nanovesicles (CNVs), that are shed from cells, have been recognized as promising indicators of health status. We analyzed the effect of long-distance running on concentration of CNVs, along with some standard blood parameters, in 27 athletes two days before and > 15 hours afte ...
Leto: 2021 Vir: Zdravstvena fakulteta (UL ZF)
Stability of erythrocyte-derived nanovesicles assessed by light scattering and electron microscopy
Darja Božič, Matej Hočevar, Matic Kisovec, Manca Pajnič, Ljubiša Pađen, Marko Jeran, Apolonija Bedina Zavec, Marjetka Podobnik, Ksenija Kogej, Aleš Iglič, Veronika Kralj-Iglič
Izvirni znanstveni članek
Oznake: sipanje svetlobe;karakterizacija veziklov;stabilnost veziklov;referenčni material zunajceličnih veziklov;nanovezikli;celični vezikli;oblika veziklov;vrstična elektronska mikroskopija zunajceličnih veziklov;krioelektronska mikroskopija zunajceličnih veziklov;light scattering;vesicle characterization;vesicle stability;extracellular vesicle reference material;nanovesicles;cellular vesicles;vesicle shape;scanning electron microscopy of extracellular vesicles;cryo-electron microscopy of extracellular vesicles;
Extracellular vesicles (EVs) are gaining increasing amounts of attention due to their potential use in diagnostics and therapy, but the poor reproducibility of the studies that have been conducted on these structures hinders their breakthrough into routine practice. We believe that a better understa ...
Leto: 2021 Vir: Zdravstvena fakulteta (UL ZF)
Autologous platelet and extracellular vesicle-rich plasma as therapeutic fluid
Kaja Troha, Domen Vozel, Matevž Arko, Apolonija Bedina Zavec, Drago Dolinar, Matej Hočevar, Zala Jan, Matic Kisovec, Boštjan Kocjančič, Ljubiša Pađen, Manca Pajnič, Samo Penič, Anna Romolo, Neža Repar, Vesna Spasovski, Nejc Steiner, Vid Šuštar, Aleš Iglič, Damjana Drobne, Ksenija Kogej, Saba Battelino, Veronika Kralj-Iglič, Veronika Kralj-Iglič
Pregledni znanstveni članek
Oznake: platelet-rich plasma;platelets;centrifugation;extracellular vesicles;small cellular particles;wound healing;regeneration;fresh-frozen plasma;intercellular signaling peptides and proteins;
The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has been explored in many medical fields with the aim to benefit from its healing potential. In parallel, efforts are being invested to understand the function and dynamics of PVRP that is complex in its composition ...
Leto: 2023 Vir: Inštitut za kovinske materiale in tehnologije (IMT)
Št. zadetkov: 8
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