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Amidochelocardin overcomes resistance mechanisms exerted on tetracyclines and natural chelocardin
Fabienne Hennessen, Marcus Miethke, Nestor Zaburannyi, Maria Loose, Tadeja Lukežič, Steffen Bernecker, Stephan Hüttel, Rolf Jansen, Judith Schmiedel, Moritz Fritzenwanker, Can Imirzalioglu, Jörg Vogel, Alexander J. Westermann, Thomas Hesterkamp, Marc Stadler, Florian Wagenlehner, Hrvoje Petković, Jennifer Herrmann, Rolf Müller
Izvirni znanstveni članek
Oznake: antibiotiki;poliketidi;tertaciklin;kelokardin;amidokelokardin;mehanizem delovanja;protimikrobna aktivnost;
The reassessment of known but neglected natural compounds is a vital strategy for providing novel lead structures urgently needed to overcome antimicrobial resistance. Scaffolds with resistance-breaking properties represent the most promising candidates for a successful translation into future thera ...
Leto: 2020 Vir: Biotehniška fakulteta (UL BF)
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