Št. zadetkov: 28
Doktorska disertacija
Oznake:
CAZymes;glycoside hydrolase;GH19;cold-activity;endolysins;sequence space;networks;enzybiotics;dissertations;
Biodiversity of organisms and their genomic content is a valuable source of enzymes, some of which can be isolated and turned into biocatalysts, useful for more sustainable and efficient industrial processes.
Organisms thriving in constantly cold environments produce enzymes that may be more effici ...
Leto:
2020
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Pregledni znanstveni članek
Oznake:
antifreeze proteins;cold adaptation;cryopreservation;food science;molecular biology;
Psychrophilic organisms adapted to cold environments produce molecules of relevance for biotechnological application, in particular enzymes active at low temperatures and ice-binding proteins that control the growth of ice crystals. The use of cold-active enzymes supports low temperature processes t ...
Leto:
2020
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
cold adaptation;enzyme stability;GDSx esterases;psychrophilic enzymes;temperature adaptation;
A key aspect of adaptation to cold environments is the production of cold‐active enzymes by psychrophilic organisms. These enzymes not only have high activity at low temperatures, but also exhibit remarkable structural flexibility and thermolability. In this context, the role of metal ions has been ...
Leto:
2023
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
cold adaptation;cold-active enzyme;endolysin;glycoside hydrolase 19;
Organisms specialized to thrive in cold environments (so-called psychrophiles) produce enzymes with the remarkable ability to catalyze chemical reactions at low temperature. Cold activity relies on adaptive changes in the proteins’ sequence and structural organization that result in high conformatio ...
Leto:
2020
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
nanobodies;HDX-MS;XL-MS;ascorbate peroxidase;
An integrative structural biology approach to identify the binding mode of a nanobody towards the pea ascorbate peroxidase
Leto:
2025
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
L-serine;oligomeric structure;phosphorylated pathway;serine deficiency disorders;serinosome;
D‐3‐phosphoglycerate dehydrogenase (PHGDH) catalyzes the NAD+‐dependent conversion of D‐3‐phospho‐glycerate to 3‐phosphohydroxypyruvate, the first step in the phosphorylated pathway for L‐serine (L‐Ser) biosynthesis. L‐Ser plays different relevant metabolic roles in eukaryotic cells: alterations in ...
Leto:
2024
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
microbial consortia;lignocellulose biomass;carbohydrate-active enzymes;phylogenetic analyses;xylanases;
The rise of agro-industrial activities over recent decades has exponentially increased lignocellulose biomasses (LCB) production. LCB serves as a cost-effective source for fermentable sugars and other renewable chemicals. This study explores the use of microbial consortia, particularly thermophilic ...
Leto:
2024
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
glycoside hydrolases;marinomonas sp. ef1;cold-active enzymes;marine bacteria;oligosaccharides;polysaccharides degradation;
Glycoside hydrolases (GHs) are pivotal in the hydrolysis of the glycosidic bonds of sugars, which are the main carbon and energy sources. The genome of Marinomonas sp. ef1, an Antarctic bacterium, contains three GHs belonging to family 3. These enzymes have distinct architectures and low sequence id ...
Leto:
2024
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
GH5;GH50;computational enzyme modelling;cold-active enzyme;
Glycoside hydrolases (GHs) are enzymes involved in the degradation of oligosaccharides and polysaccharides. The sequence space of GHs is rapidly expanding due to the increasing number of available sequences. This expansion paves the way for the discovery of novel enzymes with peculiar structural and ...
Leto:
2025
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
nanobodies;in silico engineering;mutagenesis;
CDR1 composition can affect nanobody recombinant expression yields
Leto:
2021
Vir:
Biotehniška fakulteta (UL BF)