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Št. zadetkov: 5
Spremembe v citokinskih jak/stat signalnih poteh in aktivaciji TLR4 pri otrocih s sistemskim lupusom eritematozusom in antifosfolipidnim sindromom
Marija Holcar, Tadej Avčin, Alojz Ihan
Doktorska disertacija
Oznake: pediatrija;alergija in imunologija;
Spremembe v citokinskih jak/stat signalnih poteh in aktivaciji TLR4 pri otrocih s sistemskim lupusom eritematozusom in antifosfolipidnim sindromom
Leto: 2017 Vir: Medicinska fakulteta (UL MF)
Age-related differences in percentages of regulatory and effector T lymphocytes and their subsets in healthy individuals and characteristic STAT1/STAT5 signalling response in helper T lymphocytes
Marija Holcar, Aleš Goropevšek, Alojz Ihan, Tadej Avčin
Izvirni znanstveni članek
Oznake: T lymphocytes;age-related differences;immune system;
The dynamic process of the development of the immune system can in itself result in age-related immune malfunctions. In this study, we analysed lymphocyte subsets in the peripheral blood of 60 healthy donors, divided into groups of children, adolescents, and adults, focusing on effector (Teff) and r ...
Leto: 2015 Vir: Repozitorij Univerze v Ljubljani (RUL)
Extracellular vesicle enriched miR-625-3p is associated with survival of malignant mesothelioma patients
Katja Goričar, Marija Holcar, Nina Mavec, Viljem Kovač, Metka Lenassi, Vita Dolžan
Izvirni znanstveni članek
Oznake: mezoteliom;zunajcelični vezikli;miR-625;mesothelioma;extracellular vesicles;
Malignant mesothelioma (MM) is characterized by poor prognosis and short survival. Extracellular vesicles (EVs) are membrane-bound particles released from cells into various body fluids, and their molecular composition reflects the characteristics of the origin cell. Blood EVs or their miRNA cargo m ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Urinary extracellular vesicles and their miRNA cargo in patients with Fabry nephropathy
Tina Levstek, Teo Mlinšek, Marija Holcar, Katja Goričar, Metka Lenassi, Vita Dolžan, Bojan Vujkovac, Katarina Trebušak Podkrajšek, Katarina Trebušak Podkrajšek
Izvirni znanstveni članek
Oznake: Fabry nephropathy;urinary extracellular vesicles;miRNA expression;
Current biomarkers of Fabry nephropathy lack sensitivity in detecting early kidney damageand do not predict progression of nephropathy. Urinary extracellular vesicles (uEVs) and theirmolecular cargo could reflect early changes in renal impairment as they are secreted by the cellslining the urinary t ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Characterization of plasma-derived small extracellular vesicles indicates ongoing endothelial and platelet activation in patients with thrombotic antiphospholipid syndrome
Ula Štok, Elizabeta Blokar, Metka Lenassi, Marija Holcar, Mojca Frank, Andreja Erman, Nataša Resnik, Snežna Sodin-Šemrl, Saša Čučnik, Katja Perdan-Pirkmajer, Aleš Ambrožič, Polona Žigon
Izvirni znanstveni članek
Oznake: antiphospholipid syndrome;thrombosis;adhesion molecules;
Antiphospholipid syndrome (APS) is a systemic autoimmune disease, characterized by thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL), which drive endothelial injury and thrombophilia. Extracellular vesicles (EVs) have been implicated in endothelial and thrombo ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 5
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