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Impact of deoxynivalenol and zearalenone as single and combined treatment on DNA, cell cycle and cell proliferation in HepG2 cells
Ana-Marija Domijan, Klara Hercog, Martina Štampar, Goran Gajski, Marko Gerić, Marijana Sokolović, Bojana Žegura
Izvirni znanstveni članek
Oznake: mikotoksini;deoxynivalenol;zearalenone;citotoksičnost;genotoksičnost;celični cikel;mycotoxins;comet assay;flow cytometry;co-exposure;food monitoring;
The study aimed to investigate toxicity and the mechanism of toxicity of two Fusarium mycotoxins, deoxynivalenol (DON) and zearalenone (ZEA). DON and ZEA were applied to HepG2 cells as single compounds and in combination at low environmentally relevant concentrations. HepG2 cells were exposed to DON ...
Leto: 2023 Vir: Nacionalni inštitut za biologijo (NIB)
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