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Št. zadetkov: 3
Polysaccharide-based hydrogels crosslink density equation
Tilen Kopač, Michela Abrami, Mario Grassi, Aleš Ručigaj, Matjaž Krajnc
Izvirni znanstveni članek
Oznake: gostota zamreženja;reologija;LF-NMR;hidrogelne interakcije;matematično modeliranje;crosslink density;rheology;hydrogel interactions;mathematical modeling;
A simple relation between pendant groups of polymers in hydrogels is introduced to determine the crosslink density of (complex) hydrogel systems (mixtures of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) modified nanocellulose, alginate, scleroglucan and Laponite in addition of crosslinking agents). ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Designing and mathematical modeling of pH responsive biopolymer hydrogels for targeted drug delivery in controlled release systems
Tilen Kopač, Aleš Ručigaj, Matjaž Krajnc, Aleš Podgornik, Mario Grassi
Doktorska disertacija
Oznake: hydrogel;rheology;crosslink density;polymer interactions;controlled drug release;mathematical modelling;
Targeted drug delivery to the desired site and controlled release rate increase treatment efficacy, reduce side effects and patient burden, protect the drug from degrading factors in the body, and reduce treatment costs. In this field, hydrogels are most commonly used as drug delivery systems. Fabri ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Polymer-mediated delivery of siRNAs to hepatocellular carcinoma
Rossella Farra, Francesco Musiani, Francesca Perrone, Maja Čemažar, Urška Kamenšek, Federica Tonon, Michela Abrami, Aleš Ručigaj, Mario Grassi, Gabriele Pozzato, Deborah Bonazza
Pregledni znanstveni članek
Oznake: izboljšana dostava učinkovin;onkološka zdravila;rak jeter;hepatocelularni rak;optimized drug delivery;anticancer drugs;HCC;siRNA;
Despite the advances in anticancer therapies, their effectiveness for many human tumors is still far from being optimal. Significant improvements in treatment efficacy can come from the enhancement of drug specificity. This goal may be achieved by combining the use of therapeutic molecules with tumo ...
Leto: 2018 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 3
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