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Št. zadetkov: 3
Organoidi glioblastoma razkrivajo odpornost na standardno terapijo
Bernarda Majc, Anamarija Habič, Marta Malavolta, Aleksander Sadikov, Andrej Porčnik, Jernej Mlakar, Tamara Lah Turnšek, Barbara Breznik, Metka Novak
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: glioblastom;organoidi;standardna terapija;model ex vivo;biologija raka;
Organoidi glioblastoma razkrivajo odpornost na standardno terapijo
Leto: 2023 Vir: Nacionalni inštitut za biologijo (NIB)
ǂThe ǂcytotoxic effects of cannabidiol and cannabigerol on glioblastoma stem cells may mostly involve GPR55 and TRPV1 signalling
Tamara Lah Turnšek, Bernarda Majc, Metka Novak, Ajda Sušnik, Barbara Breznik, Andrej Porčnik, Roman Bošnjak, Aleksander Sadikov, Marta Malavolta, Selma Halilčević, Jernej Mlakar, Roby Zomer
Izvirni znanstveni članek
Oznake: glioblastoma;glioma;cannabigerol;cannabidiol;cannabinoid receptors;stem cells;
Glioblastoma (GBM) is one of the most aggressive cancers, comprising 60–70% of all gliomas. The large G-protein-coupled receptor family includes cannabinoid receptors CB1, CB2, GPR55, and non-specific ion receptor protein transporters TRPs. First, we found up-regulated CNR1, GPR55, and TRPV1 express ...
Leto: 2022 Vir: Nacionalni inštitut za biologijo (NIB)
Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma
Bernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak
Izvirni znanstveni članek
Oznake: glioblastom;organoidi;monoterpeni;rak;onkologija;celična fiziologija;celična toksikologija;celična biologija;toksikologija in vitro;cellular physiology;cellular toxicology;in vitro toxicology including 3D culture;technical aspects of cell biology;cancer;
Glioblastoma (GB) is the most common primary malignant brain tumor, characterized by resistance to therapy. Despite aggressive treatment options, GB remains an incurable disease. Invasiveness and heterogeneity are key GB features that cannot be studied in preclinical in vitro models. In this study, ...
Leto: 2024 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 3
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