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Metabolic effects of SGLT2i and metformin on 3-hydroxybutyric acid and lactate in db/db mice
Makoto Harada, Siyu Han, Mengya Shi, Jianhong Ge, Shixiang Yu, Jonathan Adam, Jerzy Adamski, Markus F. Scheerer, Susanne Neschen, Martin Hrabě de Angelis
Izvirni znanstveni članek
Oznake: branched-chain amino acids;diabetic ketoacidosis;lactic acidosis;metformin adds to SGLT2i;SGLT2i monotherapy;
Combining a Sodium-Glucose-Cotransporter-2-inhibitor (SGLT2i) with metformin is recommended for managing hyperglycemia in patients with type 2 diabetes (T2D) who have cardio-renal complications. Our study aimed to investigate the metabolic effects of SGLT2i and metformin, both individually and syner ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
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