Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 5
Molecular genetic basis of the primary emotions in young adults
Timotej Glavač, Maruša Barbo, Metka Ravnik-Glavač, Maja Zupančič, Vita Dolžan
Izvirni znanstveni članek
Oznake: čustva;molekularna genetika;dopamin;serotonin;oksitocin;endogeni opioidi;nevrotrofični dejavniki;emotion;molecular genetics;dopamine;oxytocin;endogenous opioids;neurotrophic factor;
Introduction: Advances in affective neuroscience have unraveled the neurobiological underpinnings of primary emotions, making them suitable candidates for molecular genetic research. The aim of this study was to perform an exploratory molecular genetic association analysis of primary emotions in hum ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
MicroRNAs as biomarkers in spinal muscular atrophy
Maruša Barbo, Damjan Glavač, Gregor Jezernik, Metka Ravnik-Glavač, Metka Ravnik-Glavač
Pregledni znanstveni članek
Oznake: spinal muscular atrophy;SMA;circulating miRNA;biomarkers;molecular networks;
Spinal muscular atrophy (SMA) is a severe neurodegenerative disease caused by the loss of the survival motor neuron (SMN) protein, leading to degeneration of anterior motor neurons and resulting in progressive muscle weakness and atrophy. Given that SMA has a single, well-defined genetic cause, gene ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
MyomiR networks in spinal muscular atrophy
Maruša Barbo, Blaž Koritnik, Lea Leonardis, Vita Dolžan, Metka Ravnik-Glavač, Metka Ravnik-Glavač
Izvirni znanstveni članek
Oznake: SMN2 splicing;biomarkers;spinal muscular atrophy;IncRNA;miR-206;myomiR;
Disease-modifying therapies have significantly influenced the clinical course of spinal muscular atrophy (SMA), yet objective biomarkers for monitoring disease progression and treatment remain limited. We profiled four muscle-specific miRNAs (myomiRs), ten bioinformatically predicted mRNA targets, t ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Genetic variability in oxidative stress, inflammatory, and neurodevelopmental pathways: impact on the susceptibility and course of spinal muscular atrophy
Maruša Barbo, Blaž Koritnik, Lea Leonardis, Tanja Blagus, Vita Dolžan, Metka Ravnik-Glavač, Metka Ravnik-Glavač
Izvirni znanstveni članek
Oznake: inflammation;neurodegeneration;neurodevelopment;oxidative stress;single nucleotide polymorphism;spinal muscular atrophy;
The spinal muscular atrophy (SMA) phenotype strongly correlates with the SMN2 gene copy number. However, the severity and progression of the disease vary widely even among affected individuals with identical copy numbers. This study aimed to investigate the impact of genetic variability in oxidative ...
Leto: 2024 Vir: Repozitorij Univerze v Ljubljani (RUL)
Membrane damage by MBP-1 is mediated by pore formation and amplified by mtDNA
Lea Gigon, Philipp Müller, Beat Haenni, Ioan Iacovache, Maruša Barbo, Gordana Gosheva, Shida Yousefi, Alice Soragni, Christoph von Ballmoos, Benoît Zuber, Hans-Uwe Simon
Izvirni znanstveni članek
Oznake: zunajcelična past;eozinofili;glavna bazična beljakovina;metilacija DNA;tvorba por;mitohondrijske DNA;extracellular trap;eosinophils;major basic protein;DNA methylation;mitochondrial DNA;pore formation;
Eosinophils play a crucial role in host defense while also contributing to immunopathology through the release of inflammatory mediators. Characterized by distinctive cytoplasmic granules, eosinophils securely store and rapidly release various proteins exhibiting high toxicity upon extracellular rel ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 5
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: