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Št. zadetkov: 6
Effects of high relative humidity and dry purging on VOCs obtained during breath sampling on common sorbent tubes
Maxim Wilkinson, I. R. White, Royston Goodacre, Tamara M. E. Nijsen, Stephen J Fowler
Izvirni znanstveni članek
Oznake: VOCs;breath sampling;ReCIVA;
Offline breath analysis by thermal desorption gas chromatography mass spectrometry (TD-GC-MS) requires the use of sorbent traps to concentrate and store volatile compounds. The selection of which sorbent to use and best practices for managing high relative humidity are important considerations to al ...
Leto: 2020 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂmicrobiome and metabolomic signature of phases of cutaneous healing identified by profiling sequential acute wounds of human skin
Mohammed Ashrafi, Yun Xu, Howbeer Muhamadali, I. R. White, Maxim Wilkinson, Katherine Hollywood, Mohamed Baguneid, Royston Goodacre, Ardeshir Bayat
Izvirni znanstveni članek
Oznake: metabolomics;skin;volatile organic compounds;VOCs;wound healing;
Profiling skin microbiome and metabolome has been utilised to gain further insight into wound healing processes. The aims of this multi-part temporal study in 11 volunteers were to analytically profile the dynamic wound tissue and headspace metabolome and sequence microbial communities in acute woun ...
Leto: 2020 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Changes in exhaled volatile organic compounds following indirect bronchial challenge in suspected asthma
Adam Peel, Ran Wang, Waqar Ahmed, I. R. White, Maxim Wilkinson, Yoon K. Loke, Andrew M. Wilson, Stephen J Fowler
Izvirni znanstveni članek
Oznake: asthma;exhaled volatile organic compounds;pulmonology;breath metabolomics;
Background Inhaled mannitol provokes bronchoconstriction via mediators released during osmotic degranulation of inflammatory cells, and, hence represents a useful diagnostic test for asthma and model for acute attacks. We hypothesised that the mannitol challenge would trigger changes in exhaled vola ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Circadian rhythm of exhaled biomarkers in health and asthma
Maxim Wilkinson, Robert Maidstone, Andrew Loudon, John Blaikley, I. R. White, Dave Singh, David Ray Webb, Royston Goodacre, Stephen J Fowler, Hannah J. Durrington
Kratki znanstveni prispevek
Oznake: astma;cirkadiani ritem;dihanje;
Circadian rhythms control many biological processes in the body in both health and disease. Greater understanding of diurnal variability in disease related biomarkers is crucial for their application in clinical practice and biomarkers of circadian rhythm are required to facilitate further research ...
Leto: 2019 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂThe ǂpeppermint breath test
Maxim Wilkinson, I. R. White, Katie Hamshere, Olaf Holz, Sven Schuchardt, Francesca G. Bellagambi, Tommaso Lomonaco, Denise Biagini, Fabio Di Francesco, Stephen J Fowler
Izvirni znanstveni članek
Oznake: volatile organic compounds;breath;standardisation;
Exhaled breath contains hundreds of volatile organic compounds (VOCs) which offers the potential for diagnosing and monitoring a wide range of diseases. As the breath research field has grown, sampling and analytical practices have become highly varied between groups. Standardisation would allow met ...
Leto: 2021 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Breath and plasma metabolomics to assess inflammation in acute stroke
Waqar Ahmed, I. R. White, Maxim Wilkinson, Craig Johnson, Nicholas J. W. Rattray, Amit K. Kishore, Royston Goodacre, Craig J. Smith, Stephen J Fowler
Izvirni znanstveni članek
Oznake: stroke;metabolomics;breath;VOCs;inflammation;
Inflammation is strongly implicated in both injury and repair processes occurring after stroke. In this exploratory study we assessed the feasibility of repeated sampling of exhaled volatile organic compounds and performed an untargeted metabolomic analysis of plasma collected at multiple time perio ...
Leto: 2021 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 6
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