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Št. zadetkov: 4
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Zixuan Bai, Jiewen Wang, Jiaqi Liu, Haibin Yuan, Ping Wang, Miao Zhang, Yuanhang Feng, Xiangtong Cao, Xiangan Cao, Guangbo Kang, Ario De Marco, He Huang
Izvirni znanstveni članek
Oznake: nanobody rational design;bispecific binders;protein activity inhibition;
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Affinity maturation of antibody fragments
Jiaqi Liu, Guangbo Kang, Jiewen Wang, Haibin Yuan, Yili Wu, Shuxian Meng, Ping Wang, Miao Zhang, Yuli Wang, Yuanhang Feng, He Huang, Ario De Marco
Pregledni znanstveni članek
Oznake: deep learning;protein modeling;random mutagenesis;rational mutagenesis;
Affinity maturation of antibody fragments
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Analysis of the dynamic characteristics of a gear-rotor-bearing system with external excitation
Risu Na, Kaifa Jia, Shujing Miao, WeiGuo Zhang, Quan Zhang
Izvirni znanstveni članek
Oznake: rotor dynamics;external incentives;finite element method;bearing;gears;
The dynamic response of the rotor system in a ring die granulator is complex and difficult to solve when it operates under joint external, support and gear mesh forces. To solve this problem, a finite element method and extrusion theory was applied in this study to develop a dynamic coupling model f ...
Leto: 2023 Vir: Fakulteta za strojništvo (UL FS)
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
Rui Miao, Cong Jiang, Winston Y. Chang, Haiwei Zhang, Jinsu An, Felicia Ho, Pengcheng Chen, Han Zhang, Caroline Furtado Junqueira, Iva Hafner Bratkovič
Izvirni znanstveni članek
Oznake: biokemija;gasdermin D;DNK;piroptoza;
Leto: 2023 Vir: Kemijski inštitut (KI)
Št. zadetkov: 4
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