Št. zadetkov: 10
Video in druga učna gradiva
Oznake:
medicine;neuroscience
Najpogostejša oblika demence je Alzheimerjeva bolezen za katero so v Avstriji zgodnje faze testiranja cepiva pokazale obetavne rezulate. V klinični študiji, ki preučuje učinkovitost dveh različnih cepiv, sodelujejo tudi slovenski raziskovalci in pacienti. Predavala bo vodja te raziskave.
Leto:
2017
Vir:
videolectures.net
Doktorska disertacija
Oznake:
demenca;ishemična možganska kap;znotrajmožganska krvavitev;atrijska fibrilacija;antikoagulantno zdravljenje;smrt zaradi možganske kapi;
Uvod: Bolniki z demenco imajo višjo prevalenco levkoaraioze in možganskih mikrokrvavitev, ki so lahko povezane z višjim tveganjem za hemoragične zaplete ob antikoagulantnem zdravljenju (AKZ) in trombolitičnem zdravljenju ishemične možganske kapi (IMK).
Cilji: Preučiti, ali so bolniki z demenco, ki s ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
Bolezni živčevja;Disertacije;Demenca;Možganska kap;Bolnišnično zdravljenje;
Uvod: Demenca in možganska kap se pogosto pojavljata skupaj; kar 10% možganski kapi se pojavi pri bolnikih z predobstoječo demenco. Predpostavlja se, da predobstoječa demenca vpliva na zdravljenje možganske kapi in funkcijski izhod, vendar večjih raziskav, ki bi to potrdile, ni.
Cilji: Preučiti bol ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Montrealska lestvica spoznavnih sposobnosti;
Objective The Montreal cognitive assessment scale (MoCA) is commonly used for detecting individuals with mild cognitive impairment (MCI). The aim of the present study was to evaluate the validity of the Slovenian MoCA as a screening tool for MCI and to determine the optimal cut-of point to detect MC ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
neurodegenerative dementias;biomarker;FDG PET;network analysis;machine learning;neurology;
Ozadje: V najzgodnejših stopnjah nevrodegenerativnih demenc lahko diferencialna diagnoza predstavlja izziv, zaradi česar postaja uporaba bioloških označevalcev v klinični praksi in pri raziskovanju vedno pogostejša. Izboljšava trenutnih in razvoj novih bioloških označevalcev sta prioriteti v nevrozn ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Alzheimerjeva bolezen;oksidativni stres;vnetje;Alzheimer’s disease;oxidative stress;inflammation;
Oxidative stress and neuroinflammation are important processes involved in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Numerous risk factors, including genetic background, can affect the complex interplay between those mechanisms in the aging brain and can also affect typical AD ha ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Parkinson's Disease;genetic polymorphism;dopaminergic pathway;personalized medicine;adverse events;
Dopaminergic pathway is the most disrupted pathway in the pathogenesis of Parkinson's disease. Several studies reported associations of dopaminergic genes with the occurrence of adverse events of dopaminergic treatment. However, none of these studies adopted a pathway based approach. The aim of this ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Parkinson's disease;susceptibility;polymorphism;oxidative stress;inflammation;adverse events;
Background Inflammation and oxidative stress are recognized as important contributors to Parkinson's disease pathogenesis. As such, genetic variability in these pathways could have a role in susceptibility for the disease as well as in the treatment outcome. Dopaminergic treatment is effective in ma ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
nevrologija;napredovala Parkinsonova bolezen;levdopa-karbidopa gel;perkutana endoskopska gastrojujenostoma;kvaliteta življenja;stranski učinki;
Objectives: Levodopa/carbidopa intrajejunal gel (LCIG) is an effective therapeutic strategy to overcome levodopa-induced motor complications in advanced Parkinson's disease (PD). However, it requires invasive percutaneous endoscopic gastrojejunostomy (PEG-J) and may be associated with serious advers ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Parkinsonova bolezen;kognitivne motnje;paraoksonaza 1;Parkinson disease;cognitive impairment;paraoxonase 1;
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD), which often progresses to PD dementia. PD patients with and without dementia may differ in certain biochemical parameters, which could thus be used as biomarkers for PD dementia. The enzyme paraoxonase 1 (PON1) has previ ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)