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Chemo-enzymatic synthesis of viscoelastic pseudopeptidoglycan networks
Philipp Loibner, David Bučak-Gasser, Katharina Schober, Tobias Alexander Steindorfer, Monika Brandtner, Tobias Dorn, Tanja Wrodnigg, Dmytro Neshchadin, Georg Gescheidt-Demner, Matej Bračič, Florian Lackner, Tamilselvan Mohan, Karin Stana-Kleinschek, Rupert Kargl
Izvirni znanstveni članek
Oznake: biomateriali;bakterijski peptidoglikani (PG);kemo-encimska sinteza;biomaterials;bacterial peptidoglycans (PGs);chemo-enzymatic synthesis;
Bacterial peptidoglycans (PGs) are essential targets for antibiotics and immune cells. Chemical methods to reproduce PGs semisynthetically are tedious and wasteful. In this work, we describe a new approach to form pseudo-PGs (PPGs) using the protease papain and custom-made peptides conjugated to a g ...
Leto: 2025 Vir: Fakulteta za strojništvo (UM FS)
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