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Activation of α2B/2C adrenergic receptor ameliorates ocular surface inflammation through enhancing regulatory T cell function
Nai-Wen Fan, Man Yu, Shudan Wang, Tomas Blanco, Zala Lužnik, Sunil K. Chauhan, Veena Viswanath, Daniel Gil, Katherine S Held, Yihe Chen, Dana Reza
Izvirni znanstveni članek
Oznake: dry eye disease;treatment;T cells;Th17 immunity;autoimmunity;
There is an unmet need for effectively treating dry eye disease (DED), a T cell-mediated chronic, inflammatory ocular surface disorder. Given the potential of nonneuronal adrenergic system in modulating T cell response, we herein investigated the therapeutic efficacy and the underlying mechanisms of ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
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