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Št. zadetkov: 2
Phenotypic changes in Chinese hamster ovary (CHO) cells during continuous fermentation.
Jerneja Štor, Irena Golinar, Irena Golinar, Nicole Borth, Nicole Borth, Mojca Narat, Primož Rožman
Magistrsko delo
Oznake: CHO;kontinuirani bioproces;metilacija DNA;restrikcijski encimi;HpaII;MspI;fluorescein-12-dUTP;DAC;resveratrol;RNA interferenca;
CHO K1 8mM L-Gln and CHO K1 0mM L-Gln cells were cultured in a continuous culture where steady state was used to study cell activity under stable environment. Moreover, by changing the dilution rate we studied how changes in environment affect cell performance. Culture viability, viable cell density ...
Leto: 2019 Vir: Biotehniška fakulteta (UL BF)
Fermentation of CHO cells for biomass component quantification
Špela Knez, Mojca Narat, Nicole Borth
Magistrsko delo
Oznake: biotechnology;bioprocessing;modeling;biomass;
Chinese Hamster Ovary (CHO) cells are the main production host for recombinant therapeutic proteins. They have desirable process performance characteristics such as high expression rates, rapid growth and required post- translational modification. To further exploit its potential, genome scale ...
Leto: 2019 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 2
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