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Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids
Goran Poje, Davor Šakić, Marina Marinovich, Jiangyang You, Michael Tarpley, Kevin P. Williams, Nikolina Golub, Jaka Dernovšek, Tihomir Tomašić, Erim Bešić, Zrinka Rajić
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Oznake: harmine;β-carboline;ferrocene;hybrid compounds;antiproliferative activity;glioblastoma multiforme;Hsp90;DYRK1A;antioxidant activity;EPR spectroscopy;
The poor prognosis of glioblastoma multiforme, inadequate treatment options, and growing drug resistance urge the need to find new effective agents. Due to the significant anti-cancer potential of harmicens, hybrid compounds which comprise harmine/β-carboline and ferrocene moiety, we investigated th ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
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