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Št. zadetkov: 2
Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development
Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Blaž Zupan, Gad Shaulsky
Izvirni znanstveni članek
Oznake: genska pot zelene brade;medsebojna genska inhibicija;analiza transkriptomskih podatkov;greenbeard pathway;mutual suppression;transcriptome data analysis;
Background The Dictyostelium greenbeard pathway is mediated by two polymorphic transmembrane proteins,the TgrC1 ligand and the TgrB1 receptor. These proteins mediate allorecognition, altruism, and the developmental transition to multicellularity. A genetic suppressor screen revealed activating mut ...
Leto: 2025 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Early cAMP signaling orchestrates single-cell synchronicity throughout Dictyostelium development
Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Rui Chen, Yumei Li, Blaž Zupan, Gad Shaulsky
Izvirni znanstveni članek
Oznake: cAMP signalizacija;Dictyostelium discoideum;sinhronost celic;razvoj;transkriptomika;cAMP;cell synchronicity;development;transcriptomics;
Synchronicity is observed in many biological systems, including development, as seen in vertebrate body axis formation, fly eye development, and development of the social amoeba D. discoideum. Despite its prevalence, quantitative analyses of synchronicity at the single-cell level remain rare. Here w ...
Leto: 2026 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Št. zadetkov: 2
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