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Direct tumor-adipocyte contact as a prognostic biomarker in resected pancreatic ductal adenocarcinoma
Michael Günther, Konstantin Bräutigam, Martin Wartenberg, Muhammed D. Arslan, Robert Sucher, Mohamed El-Mahrouk, Jens Neumann, Przemyslaw Grochowski, Anna S. Wenning, Beat Gloor, Berna Dornieden, Robert Grützmann, Christian Pilarsky, Arndt Hartmann, Markus Eckstein, Bruno Märkl, Christian Matek, Kristijan Skok, Steffen Ormanns, Nic G. Reitsam
Izvirni znanstveni članek
Oznake: adenocarcinoma;adipose tissue;multicenter;PDAC;pancreas;prognosis;SARIFA;tumor microenvironment;tumor-adipocyte-contact;
Background: Direct tumor-adipocyte contact (TAC), also referred to as Stroma AReactive Invasion Front Areas (SARIFA), is an emerging histomorphologic biomarker, defined by histologically visible direct tumor-adipocyte interaction. Its prognostic relevance in pancreatic ductal adenocarcinoma (PDAC) h ...
Leto: 2026 Vir: Medicinska fakulteta (UM MF)
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