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Št. zadetkov: 3
Spaceflight on the ISS changed the skeletal muscle proteome of two astronauts
Marta Murgia, Joern Rittweger, Carlo Reggiani, Roberto Bottinelli, Matthias Mann, Stefano Schiaffino, Marco Narici
Izvirni znanstveni članek
Oznake: skeletne mišice;mikrogravitacija;atrofija mišic;avtofagija;skeletal muscles;microgravity;muscle atrophy;autophagy;
Skeletal muscle undergoes atrophy and loss of force during long space missions, when astronauts are persistently exposed to altered gravity and increased ionizing radiation. We previously carried out mass spectrometry-based proteomics from skeletal muscle biopsies of two astronauts, taken before and ...
Leto: 2024 Vir: Univerza na Primorskem (UP)
Pathophysiological mechanisms of reduced physical activity
Fabio Sarto, Roberto Bottinelli, Martino V. Franchi, Simone Porcelli, Boštjan Šimunič, Rado Pišot, Marco Narici
Pregledni znanstveni članek
Oznake: telesna neaktivnost;inzulinska občutljivost;physical inactivity;cage reduction;insulin sensitivity;muscle atrophy;
Physical inactivity represents a heavy burden for modern societies and is spreading worldwide, it is a recognised pandemic and is the fourth cause of global mortality. Not surprisingly, there is an increasing interest in longitudinal studies on the impact of reduced physical activity on different ph ...
Leto: 2023 Vir: Univerza na Primorskem (UP)
Preserved mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults
Evgeniia Motanova, Lucrezia Zuccarelli, Evgenii Lysenko, Stefano Amoretti, Marco Pirazzini, Ornella Rossetto, Lorenza Brocca, Roberto Bottinelli, Maria Antonietta Pellegrino, Giovanni Baldassarre, Clarissa Gissi, Giovanna Lippe, Mladen Gasparini, Boštjan Šimunič, Rado Pišot, Bruno Grassi, Marco Narici
Izvirni znanstveni članek
Oznake: skeletal muscle;mitochondria;older adults;physical inactivity;mitochondrial respiration;
Ageing affects mitochondrial integrity in skeletal muscle, and physical inactivity may further exacerbate these changes. Although mitochondrial alterations are documented in ageing and disuse independently, how disuse impacts the mitochondrial phenotype in older populations remains unclear. This wor ...
Leto: 2026 Vir: Repozitorij Univerze na Primorskem (RUP)
Št. zadetkov: 3
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