Št. zadetkov: 20
Doktorska disertacija
Oznake:
Mycoplasma pneumoniae;epidemiologija;genotipizacija;patogeneza;citotoksičnost;imunski odziv;
V raziskavi smo želeli ugotoviti pojavnost okužb dihal povzročenih z bakterijo M. pneumoniae pri slovenskih bolnikih v obdobju desetih let, spoznati kateri genotipi so bili v tem obdobju navzoči ter proučiti, če obstajajo med posameznimi genotipi razlike v patogenosti in vitro. Pregledali smo podatk ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
protivirusno testiranje;laški smilj (Helichrysum italicum);HeLa;AdV5;MHV;citotoksičnost;test plakov;CPE;TCID50;
Virusne okužbe predstavljajo velik izziv sodobne medicine zaradi naraščajoče odpornosti virusov in omejenega števila učinkovitih zdravil. Zdravilna rastlina laški smilj (Helichrysum italicum) je pomemben vir bioaktivnih molekul s potencialom za razvoj novih terapevtikov. V magistrskem delu smo upora ...
Leto:
2025
Vir:
Biotehniška fakulteta (UL BF)
Izvirni znanstveni članek
Oznake:
nasopharyngeal swab;collection procedure;sample quality;
A nasopharyngeal swab (NPS) is the most frequently collected sample type when molecular diagnosis of respiratory viruses, including SARS CoV-2, is required. An optimal collection technique would provide sufficient sample quality for the diagnostic process and would minimize the discomfort felt by th ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
bioinformatics workflow;clinical metagenomics;long reads;pathogen detection;short PE reads;
Over the past decade, there have been many improvements in the field of metagenomics, including sequencing technologies, advances in bioinformatics and the development of reference databases, but a one-size-fits-all sequencing and bioinformatics pipeline does not yet seem achievable. In this study, ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
SARS-CoV-2;nasopharyngeal swab;saliva;
A prospective cohort study was conducted during the Delta and Omicron severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) epidemic waves from paired nasopharyngeal swab (NPS or NP swab) and saliva samples taken from 624 participants. The study aimed to assess if any differences among p ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
SARS-CoV2;molecular analyzer;Abbott's Alinity M;
Abbott's Alinity m is a recently launched fully integrated, automated molecular analyzer allowing continuous loading of samples and sample-to-result molecular detection of several microorganisms. Manufacturer-independent clinical evaluation of Alinity m SARS-CoV-2 (Alinity) against cobas 6800 SARS-C ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
respiratory viruses;validation;molecular assay;
The clinical symptoms caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are nonspecific and can be associated with most other respiratory viruses that cause acute respiratory tract infections (ARI). Because the clinical differentiation of COVID-19 patients from those with ot ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
16S rRNA metabarcoding;bioinformatics;campylobacter;metagenomics;NGS;
Objective: This study aimed to employ advanced bioinformatics and modern sequencing approaches to solve a diagnostic problem of persistent Campylobacter spp. molecular detection yet negative culture results from four consecutive stool samples of a previously healthy patient with newly diagnosed sele ...
Leto:
2025
Vir:
Repozitorij Univerze v Ljubljani (RUL)
Maša Knežević,
Dobrica Rončević,
Darija Vukić Lušić,
Mirna Mihelčić,
Rok Kogoj,
Darja Keše,
Marin Glad,
Arijana Cenov,
Mateja Ožanič,
Daniela Glažar Ivče,
Marina Šantić
Izvirni znanstveni članek
Oznake:
Acanthamoeba;environment;infection;Legionella;
Legionellae are gram-negative bacteria most commonly found in freshwater ecosystems and purpose-built water systems. In humans, the bacterium causes Legionnaires’ disease (LD) or a Pontiac fever. In this study, the different waters (drinking water, pool water, cooling towers) in which Legionella pne ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Jan Slunečko,
Rok Kogoj,
Samo Zakotnik,
Alen Suljič,
Nataša Knap,
Martin Bosilj,
Franc Strle,
Tatjana Avšič-Županc,
Petra Bogovič,
Petra Bogovič,
Miša Korva,
Miša Korva
Izvirni znanstveni članek
Oznake:
mNGS;clinical metagenomics;molecular diagnostics;universal pathogen detection;enhanced RNA virus detection;
Introduction: Blood culture is the cornerstone of microbiological diagnostics for patients with acute undifferentiated fever and no obvious localization of infection; however, up to 50% of cases remain undiagnosed. Infections caused by arboviruses, fastidious or even uncultivable bacteria, or parasi ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)