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Št. zadetkov: 2
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease
Matthias Arnold, Mustafa Buyukozkan, P. Murali Doraiswamy, Kwangsik Nho, Tong Wu, Vilmundur Gudnason, Lenore J. Launer, Rui Wang-Sattler, Jerzy Adamski, Philip L. De Jager
Izvirni znanstveni članek
Oznake: bioenergetic capacity;resilience;Alzheimer's disease;bioenergetska zmogljivost;odpornost;Alzheimerjeva bolezen;
Impaired glucose uptake in the brain is one of the earliest presymptomatic manifestations of Alzheimer's disease (AD). The absence of symptoms for extended periods of time suggests that compensatory metabolic mechanisms can provide resilience. Here, we introduce the concept of a systemic 'bioenerget ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort
Juliane Maushagen, Nuha Shugaa Addin, Christopher Schuppert, Cavin K Ward-Caviness, Johanna Nattenmüller, Jerzy Adamski, Annette Peters, Fabian Bamberg, Christopher L Schlett, Rui Wang-Sattler
Izvirni znanstveni članek
Oznake: cardiac function;cardiac morphology;cardiovascular disease;imaging;left ventricle;metabolites;population-based;
Background: Changes in serum metabolites in individuals with altered cardiac function and morphology may exhibit information about cardiovascular disease (CVD) pathway dysregulations and potential CVD risk factors. We aimed to explore associations of cardiac function and morphology, evaluated using ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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