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Synthesis, molecular docking, and neuroprotective effect of 2-methylcinnamic acid amide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) - an induced Parkinson’s disease model
Maya Chochkova, Rusi Rusew, Reni Kalfin, Lyubka Tancheva, Maria Lazarova, Hristina Sbirkova-Dimitrova, Andrey Popatanasov, Krasimira Tasheva, Boris Shivachev, Nejc Petek, Martin Štícha
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Oznake: amantadin;2-metilcimetna kislina;rentgenska difrakcija monokristalov;Parkinsonova bolezen;amantadine;2-methylcinnamic acid;single crystal X-ray diffraction;Parkinson's disease;
Parkinson’s disease (PD) has emerged as the second most common form of human neurodegenerative disorders. However, due to the severe side effects of the current antiparkinsonian drugs, the design of novel and safe compounds is a hot topic amongst the medicinal chemistry community. Herein, a convenie ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
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