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ǂThe ǂcomparison of melt technologies based on mesoporous carriers for improved carvedilol dissolution
Mila Kovačević, Amrit Paudel, Odon Planinšek, Serena Bertoni, N. Passerini, Ožbej Zupančič, Carolina Alva, Ilija Ilić, Alenka Zvonar
Izvirni znanstveni članek
Oznake: mesoporous carrier;melt granulation;hot melt extrusion;PEG 6000;Soluplus;amorphous solid dispersion;
High-shear (HS) melt granulation and hot melt extrusion (HME) were compared as perspective melt-based technologies for preparation of amorphous solid dispersions (ASDs). ASDs were prepared using mesoporous carriers (Syloid® 244FP or Neusilin® US2), which were loaded with carvedilol dispersed in poly ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
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