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Št. zadetkov: 3
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Oznake:
The present article gives a brief overview on the use of altered hepatic foci (AHF) and aberrant crypt foci (ACF) in the colon in experimental cancer research. These foci are easily detectable preneoplastic lesions, which have been discovered approximately 30 years ago. AHF and ACF are valuable tool ...
Leto: 2004 Vir: dLib.si Digitalna knjižnica Slovenije
Izvirni znanstveni članek
Oznake: ACF;SCGE;xanthohumol;phases IandIIenzymes;
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ)
Leto: 2010 Vir: Repozitorij Univerze v Ljubljani (RUL)
Izvirni znanstveni članek
Oznake: hepatic cell lines;p53;comet assay;genotoxicity;
Cell lines which are currently used in genotoxicity tests lack enzymes which activate/detoxify mutagens. Therefore, rodent-derived liver preparations are used which reflect their metabolism in humans only partly; as a consequence misleading results are often obtained. Previous findings suggest that ...
Leto: 2018 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 3
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