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Toxicological profile of nanostructured bone substitute based on hydroxyapatite and poly(lactide-co-glycolide) after subchronic oral exposure of rats
Smiljana Paraš, Dijana Trišić, Olivera Mitrović Ajtić, Bogomir Prokić, Damjana Drobne, Slavoljub Živković, Vukoman Jokanović
Izvirni znanstveni članek
Oznake: biokemija;genotoksičnost;kostni nadomestki;nanomateriali;hydroxyapatite;bone substitute;genotoxicity;subchronic toxicity;biocompatibility;
Novel three-dimensional (3D) nanohydroxyapatite-PLGA scaffolds with high porosity was developed to better mimic mineral component and microstructure of natural bone. To perform a final assessment of this nanomaterial as a potential bone substitute, its toxicological profile was particularly investig ...
Leto: 2020 Vir: Biotehniška fakulteta (UL BF)
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