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Št. zadetkov: 7
Ovrednotenje in optimizacija uporabe celičnega biosenzorskega sistema humanih jetrnih celic HepG2p21 DsRed za detekcijo genotoksičnih snovi
Tanja Blagus, Maja Čemažar
Diplomsko delo
Oznake: celična linija Hepg2;biosenzorski sistem;fluorescenčni protein DsRed;promotor p21;genotoksičnost;test Alamar Blue;izražanje poročevalskega proteina;
Ovrednotenje in optimizacija uporabe celičnega biosenzorskega sistema humanih jetrnih celic HepG2p21 DsRed za detekcijo genotoksičnih snovi
Leto: 2011 Vir: Repozitorij Univerze v Ljubljani (RUL)
Serotonin-related functional genetic variants affect the occurrence of psychiatric and motor adverse events of dopaminergic treatment in Parkinson’s disease
Sara Redenšek, Tanja Blagus, Maja Trošt, Vita Dolžan, Vita Dolžan
Izvirni znanstveni članek
Oznake: Parkinsonova bolezen;motorični zapleti;vizualne halucinacije;Parkinson’s disease;motor complications;visual hallucinations;
The serotonergic system is important in Parkinson’s disease (PD) pathogenesis as it can take over dopamine production after a large portion of dopaminergic neurons is lost through neurodegeneration. The aim of this study was to evaluate the effect of genetic variability of serotonergic genes on the ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Genetic variability of the vitamin D receptor affects susceptibility to Parkinson's disease and dopaminergic treatment adverse events
Sara Redenšek, Tilen Kristanc, Tanja Blagus, Maja Trošt, Vita Dolžan
Izvirni znanstveni članek
Oznake: nevrologija;Parkinsonova bolezen;receptor vitamina D;nevroznanost;
Vitamin D is a lipid-soluble molecule and an important transcriptional regulator in many tissues and organs, including the brain. Its role has been demonstrated also in Parkinson’s disease (PD) pathogenesis. Vitamin D receptor (VDR) is responsible for the initiation of vitamin D signaling cascade. T ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Association of genetic polymorphisms in oxidative stress and inflammation pathways with glaucoma risk and phenotype
Makedonka Atanasovska-Velkovska, Katja Goričar, Tanja Blagus, Vita Dolžan, Barbara Cvenkel
Izvirni znanstveni članek
Oznake: glaucoma;inflammation;oxidative stress;
Oxidative stress and neuroinflammation are involved in the pathogenesis and progression of glaucoma. Our aim was to evaluate the impact of selected single-nucleotide polymorphisms in inflammation and oxidative stress genes on the risk of glaucoma, the patients' clinical characteristics and the glauc ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Biological properties of melanoma and endothelial cells after plasmid AMEP gene electrotransfer depend on integrin quantity on cells
Maša Bošnjak, Lara Prosen, Tanja Dolinšek, Tanja Blagus, Boštjan Markelc, Maja Čemažar, Céline Bouquet, Gregor Serša
Objavljeni znanstveni prispevek na konferenci
Oznake: antiangiogenic;integrins;gene electrotransfer;human endothelial cells;murine melanoma cells;plasmid AMEP;
The data on the biological responsiveness of melanoma and endothelial cells that are targeted by Antiangiogenic MEtargidin Peptide (AMEP) are limited; therefore, the antiproliferative, antimetastatic and antiangiogenic effects of AMEP were investigated in murine melanoma and human endothelial cells ...
Leto: 2013 Vir: Fakulteta za vede o zdravju (UP FVZ)
Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity
Aleš Sedlar, Tanja Dolinšek, Boštjan Markelc, Lara Prosen, Simona Kranjc, Maša Bošnjak, Tanja Blagus, Maja Čemažar, Gregor Serša
Izvirni znanstveni članek
Oznake: Drug therapy;Electroporation;elektrokemoterapija;Gene transfer;Interleukin-12;Neoplasms, experimental;rak (medicina);Therapy cisplatin;Treatment out;zdravljenje
Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity
Leto: 2012 Vir: Onkološki inštitut Ljubljana (OI)
Early cardiotoxicity after adjuvant concomitant treatment with radiotherapy and trastuzumab in patients with breast cancer
Tanja Marinko, Simona Borštnar, Rok Blagus, Jure Dolenc, Cvetka Bilban-Jakopin
Izvirni znanstveni članek
Oznake: radiotherapy;adjuvant radiotherapy;cardiotoxicity;breast cancer;
Z raziskavo smo želeli preveriti ali je med bolnicami, ki so ob zdravljenju s trastuzumabom pooperativno obsevale levo (skupina 1) oziroma desno (skupina 2) dojko/prsno steno, po zaključenem zdravljenju pomembna razlika v zgodnjih kazalcih kardiotoksičnosti. To smo merili z iztisnim deležem levega p ...
Leto: 2018 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 7
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