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Št. zadetkov: 3
Perforin activity at membranes leads to invaginations and vesicle formation
Tilen Praper, Aleš Kladnik, Gregor Anderluh
Izvirni znanstveni članek
Oznake: perforin;mambranes (biology);vesicles;
The cytotoxic cell granule secretory pathway is essential for immune defence. How the pore-forming protein perforin (PFN) facilitates the cytosolic delivery of granule-associated proteases (granzymes) remains enigmatic. Here we show that PFN is able to induce invaginations and formation of complete ...
Leto: 2011 Vir: Biotehniška fakulteta (UL BF)
Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH
Tilen Praper, Mojca Podlesnik Beseničar, Helena Istinič, Zdravko Podlesek, Sunil Metkar, Christopher J. Froelich, Gregor Anderluh
Izvirni znanstveni članek
Oznake: perforin;MACPF domain;pore forming proteins;pH-dependence;surface plasmon resonance;
Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH
Leto: 2010 Vir: Biotehniška fakulteta (UL BF)
Human perforin employs different avenues to damage membranes
Tilen Praper, Andreas F.- P. Sonnen, Gabriella Viero, Aleš Kladnik, Christopher J. Froelich, Gregor Anderluh, Mauro Dalla Serra, Robert J. Gilbert
Izvirni znanstveni članek
Oznake:
Human perforin employs different avenues to damage membranes
Leto: 2011 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 3
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