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There are many challenges in computational modeling of biological processes. Few processes such as signaling pathways operate in- dependently of others but rather involve substantial coordination and shared resources. The level of abstraction appropriate for understand- ing different processes, e.g, ...

Most engineering and science problems involve modeling. We need inference calculations to draw predictions from the models or to estimate them from available measurements. In many cases the inference calculations can be done only approximately as in decoding, sensor networks, or in modeling biologic ...