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Simvastatin is effective in killing the radioresistant breast carcinoma cells
Bertram Aschenbrenner, Giulia Negro, Dragana Savic, Maxim Sorokin, Anton A. Buzdin, Ute Maria Ganswindt, Maja Čemažar, Gregor Serša, Sergej Skvortsov, Ira Skvortsova
Izvirni znanstveni članek
Oznake: radiotherapy;breast cancer;radioresistant cells;
Background. Statins, small molecular 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, are widely used to lower cholesterol levels in lipid-metabolism disorders. Recent preclinical and clinical studies have shown that statins exert beneficial effects in the management of breast cancer by i ...
Leto: 2021 Vir: Onkološki inštitut Ljubljana (OI)
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