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Development of novel aza-stilbenes as a new class of selective MAO-B inhibitors for the treatment of Parkinson’s disease
Damijan Knez, Fen Wang, Wen-Xiang Duan, Martina Hrast, Stanislav Gobec, Xiao-Yu Cheng, Xiao-Bo Wang, Cheng-Jie Mao, Chun-Feng Liu, Rok Frlan
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Oznake: neurodegenerative diseases;Parkinson’s disease;monoamine oxidase B;inhibitors;azastilbene;library;
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a progressive loss of nigrostriatal dopaminergic neurons. Inhibitors of monoamine oxidase B (MAO-B) have shown promise in alleviating motor symptoms and reducing oxidative stress associated with PD. In this study, we report th ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
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