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Št. zadetkov: 3
QSAR analysis of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase
Ke-Xian Chen, Hai-Ying Xie, Zu-Guang Li
Izvirni znanstveni članek
Oznake: organska kemija;hepatitis C;virusi;polimeraze;genetski algoritmi;
QSAR analysis of 1,1-dioxoisothiazole and benzobthiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase
Leto: 2009 Vir: dLib.si Digitalna knjižnica Slovenije
Study on the trade-off mechanism between flow field uniformity and turbulent pressure pulsations in back-pressure matching for supersonic wind tunnels
Peng Liu, Jinglun Cai, Hui Jin, Yibing Yin, Ludi Kang, Xian Chen
Izvirni znanstveni članek
Oznake: supersonic wind tunnel;backpressure matching;flow field uniformity;pressure pulsation;shear layer;
Supersonic wind tunnel testing is critical for aircraft aerodynamic configuration validation, where test chamber flow uniformity and turbulent pressure pulsations are core determinants of test data reliability. Existing back-pressure matching studies only optimize flow uniformity as a single objecti ...
Leto: 2026 Vir: Fakulteta za strojništvo (UL FS)
Development and characterization of CR101-ADC, a fully-human anti-claudin18.2 monoclonal antibody-drug conjugate
Miao Zhang, Haibin Yuan, Xian Li, Jianan Yin, Fei Qi, Junjie Chen, Jiatao Zhou, Xiaolong Wang, Shuping Zhang, Ario De Marco
Izvirni znanstveni članek
Oznake: claudin 18.2;antibody-drug conjugate;tumor therapy;
Claudin18.2 (CLDN18.2) is a stomach-specific tight junction protein aberrantly exposed in multiple cancers, particularly gastric and pancreatic malignancies, making it an attractive therapeutic target. Here, we developed CR101-ADC, a novel antibody-drug conjugate (ADC) constructed from a fully human ...
Leto: 2026 Vir: Univerza v Novi Gorici (UNG)
Št. zadetkov: 3
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