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Št. zadetkov: 3
IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis
Marchien G. Dallinga, Yasmin I. Habani, Richelle P. Kayser, Cornelis J. F. van Noorden, Ingeborg Klaassen, Reinier O. Schlingemann
Izvirni znanstveni članek
Oznake: biokemija;angiogeneza;celice;beljakovine;Angiogenesis;tip cells;IGF2;IGF binding proteins;endothelial cells;cultured cells;endothelial growth factors;
Purpose We have previously identified insulin-like growth factor 2 (IGF2) and insulin-like growth factor 1 receptor (IGF1R) as essential proteins for tip cell maintenance and sprouting angiogenesis. In this study, we aim to identify other IGF family members involved in endothelial sprouting angioge ...
Leto: 2020 Vir: Nacionalni inštitut za biologijo (NIB)
ǂThe ǂrole of heparan sulfate and neuropilin 2 in VEGFA signaling in human endothelial tip cells and non-tip cells during angiogenesis in vitro
Marchien G. Dallinga, Yasmin I. Habani, Alinda W. M. Schimmel, Geesje M. Dallinga-Thie, Cornelis J. F. van Noorden, Ingeborg Klaassen, Reinier O. Schlingemann
Izvirni znanstveni članek
Oznake: endothelial cells;angiogenesis;VEGFA;tip cells;SULF2;NRP2;HSPG;
During angiogenesis, vascular endothelial growth factor A (VEGFA) regulates endothelial cell (EC) survival, tip cell formation, and stalk cell proliferation via VEGF receptor 2 (VEGFR2). VEGFR2 can interact with VEGFR2 co-receptors such as heparan sulfate proteoglycans (HSPGs) and neuropilin 2 (NRP2 ...
Leto: 2021 Vir: Nacionalni inštitut za biologijo (NIB)
Diferential roles of eNOS in late efects ofVEGF‑A on hyperpermeability in diferent types of endothelial cells
Esmeralda K. Bosma, Shahan Darwesh, Yasmin I. Habani, Maxime Cammeraat, Paola Serrano Martinez, Mathilda E. van Breest Smallenburg, JiaY. Zheng, Ilse M.C. Vogels, Cornelis J. F. van Noorden, Reinier O. Schlingemann, Ingeborg Klaassen
Izvirni znanstveni članek
Oznake: endocytosis;RNAi;hyperpermeability;
Vascular endothelial growth factor (VEGF)-A induces endothelial hyperpermeability, but the molecular pathways remain incompletely understood. Endothelial nitric oxide synthase (eNOS) regulates acute efects of VEGF-A on permeability of endothelial cells (ECs), but it remains unknown whether and how e ...
Leto: 2023 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 3
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