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Existing cost-sensitive learning methods require that the unequal misclassification costs should be given as precise values. In many real-world applications, however, it is generally difficult to have a precise cost value since the user maybe only knows that one type of mistake is much more severe t ...

The ubiquitous cyclic di-GMP (c-di-GMP) network is highly redundant with numerous GGDEF domain proteins as diguanylate cyclases and EAL domain proteins as c-di-GMP specific phosphodiesterases comprising those domains as two of the most abundant bacterial domain superfamilies. One hallmark of the c-d ...