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Št. zadetkov: 3
Effect of upstream sequence modifications in pET vectors on the yield of recombinant proteins
Urša Štrancar, Lucia Cikatricisová, Zichen Wang, Mirna Nakić, Anneleen Olbrechts, Martine Vanhoucke, He Huang, Ario De Marco
Izvirni znanstveni članek
Oznake: recombinant protein;expression vectors;E. coli;
Increasing the yield of recombinant proteins can save time and materials and, consequently, any strategy that seems promising for achieving this objective is worth investigating. Lately, it has been proposed that modifications of upstream sequences from pET vectors would enhance the transcription ef ...
Leto: 2027 Vir: Univerza v Novi Gorici (UNG)
Noncanonical amino acid-aided synthesis of anti-PD-L1 bispecific nanobody for colon cancer immunotherapy
Xinyu Hu Hu, Ling Jiang, Haibin Yuan, Wanyi Chen, Yufei Guo, Mengxue Gao, Yijia Song, Zichen Wang, Yuli Wang, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobody;immunotherapy;PD-L1;non-canonical amino-acids;
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality, and the incidence of early-onset colon cancer has been increasing globally in recent years. The development of immunotherapies for colon cancer is critical for providing new treatment strategies to combat drug resist ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Dual-mechanism anti-CD73 antibodies CR201 and CR202 targeting distinct domains for cancer immunotherapy
Miao Zhang, Haibin Yuan, Xindi Pan, Xian Li, Zichen Wang, Shuping Zhang, Zhigang Gu, Biao Hu, Xuedong Qu, Ario De Marco
Izvirni znanstveni članek
Oznake: cancer immunotherapy;anti-CD73 antibodies;adenosine signal;
Leto: 2026 Vir: Univerza v Novi Gorici (UNG)
Št. zadetkov: 3
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