ǂan ǂinternational overview and consensus recommendations
Lene Heise Garvey (Author), Pascale Dewachter (Author), David L. Hepner (Author), Paul Michel Mertes (Author), Susanna Voltolini (Author), Russel C. Clarke (Author), Peter J. Cooke (Author), Tomaz Garcez (Author), Anne Berit Guttormsen (Author), D. Ebo (Author), Philip M. Hopkins (Author), Peter Kopač (Author)

Abstract

Suspected perioperative allergic reactions are rare but can be life-threatening. The diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct treatment is necessary to ensure a good outcome. A group of 26 international experts in perioperative allergy (anaesthesiologists, allergists, and immunologists) contributed to a modified Delphi consensus process, which covered areas such as differential diagnosis, management during and after anaphylaxis, allergy investigations, and plans for a subsequent anaesthetic. They were asked to rank the appropriateness of statements related to the immediate management of suspected perioperative allergic reactions. Statements were selected to represent areas where there is a lack of consensus in existing guidelines, such as dosing of epinephrine and fluids, the management of impending cardiac arrest, and reactions refractory to standard treatment. The results of the modified Delphi consensus process have been included in the recommendations on the management of suspected perioperative allergic reactions. This paper provides anaesthetists with an overview of relevant knowledge on the immediate and postoperative management of suspected perioperative allergic reactions based on current literature and expert opinion. In addition, it provides practical advice and recommendations in areas where consensus has been lacking in existing guidelines.

Keywords

alergijske reakcije;preobčutljivostna reakcija;epinefrin;perioperativna anafilaksija;alergijsko testiranje;allergic reactions;hypersensitivity reaction;adrenaline;perioperative anaphylaxis;allergy testing;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Publisher: Elsevier
UDC: 616-097
COBISS: 2048510577 Link will open in a new window
ISSN: 1471-6771
Parent publication: British journal of anaesthesia
Views: 913
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Other data

Secondary keywords: Allergy and immunology;Drug hypersensitivity;Anesthesia;Drug-related side effects and adverse reactions;Anaphylaxis;Epinephrine;Delphi technique;Perioperative period;Alergija in imunologija;Preobčutljivost za zdravila;Anestezija;Stranski in škodljivi učinki zdravil;Anafilaksija;Adrenalin;Delfska študija;Perioperativno obdobje;Guideline;Smernica;
Source comment: Soavtor iz Slovenije: Peter Kopac; Nasl. z nasl. zaslona; Opis vira z dne 5. 6. 2019;
Pages: str. e50-e64
Volume: ǂVol. ǂ123
Issue: ǂiss. ǂ1
Chronology: Jul. 2019
DOI: 10.1016/j.bja.2019.04.044
ID: 12066575