narrative review and consensus recommendations
Louise C. Savic (Author), David A. Khan (Author), Peter Kopač (Author), Russel C. Clarke (Author), Peter J. Cooke (Author), Pascale Dewachter (Author), D. Ebo (Author), Tomaz Garcez (Author), Lene Heise Garvey (Author), Anne Berit Guttormsen (Author)

Abstract

Unsubstantiated penicillin-allergy labels are common in surgical patients, and can lead to significant harm through avoidance of best first-line prophylaxis of surgical site infections and increased infection with resistant bacterial strains. Up to 98% of penicillin-allergy labels are incorrect when tested. Because of the scarcity of trained allergists in all healthcare systems, only a minority of surgical patients have the opportunity to undergo testing and de-labelling before surgery. Testing pathways can be modified and shortened in selected patients. A variety of healthcare professionals can, with appropriate training and in collaboration with allergists, provide testing for selected patients. We review how patients might be assessed, the appropriate testing strategies that can be used, and the minimum standards of safe testing.

Keywords

provokacijsko testiranje za zdravila;operacije;drug provocation testing;surgical procedures;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Publisher: Elsevier
UDC: 616-097
COBISS: 2048508529 Link will open in a new window
ISSN: 1471-6771
Parent publication: British journal of anaesthesia
Views: 854
Downloads: 261
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Other data

Secondary keywords: Allergy and immunology;Drug hypersensitivity;Penicillins;Antibiotic prophylaxis;Surgery;Surgical procedures, operative;Bacterial infections;Surgical wound infection;Alergija in imunologija;Preobčutljivost za zdravila;Penicilini;Antibiotična profilaksa;Kirurgija;Operativni kirurški postopki;Bakterijske okužbe;Okužbe kirurških ran;
Source comment: Soavtor iz Slovenije: P. Kopac; Nasl. z nasl. zaslona; Opis vira z dne 31. 5. 2019;
Pages: str. e82-e94
Volume: ǂVol. ǂ123
Issue: ǂiss. ǂ1
Chronology: Jul. 2019
DOI: 10.1016/j.bja.2019.01.026
ID: 12080812