Jaka Mur (Author), Vid Agrež (Author), Jaka Petelin (Author), Rok Petkovšek (Author)

Abstract

Precise excitation of cavitation is a promising mechanism for microsurgery procedures and targeted drug delivery enhancement. The underlying phenomenon of interest, jetting behaviour of oscillating cavitation bubbles, occurs due to near-surface interactions between the boundary, liquid, and bubble. Within this study we measured boundary effects on the cavitation bubble dynamics and morphology, with an emphasis on observation and measurement of jetting behaviour near tissue-phantom biointerfaces. An important mechanism of boundary poration has been observed using time-resolved optical microscopy and explained for different tissue-phantom surface densities and Young’s modulus. Below a critical distance to the boundary, around γ = 1.0, the resulting jets penetrated the tissue-phantom, resulting in highly localized few micrometer diameter jets.

Keywords

cavitation bubbles;laser breakdown;tissue phantom;sonoporation;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UL FS - Faculty of Mechanical Engineering
UDC: 532.528
COBISS: 97105923 Link will open in a new window
ISSN: 2156-7085
Views: 321
Downloads: 112
Average score: 0 (0 votes)
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Other data

Secondary language: Slovenian
Secondary keywords: kavitacijski mehurčki;laserski preboj;tkivni fantom;sonoporacija;
Type (COBISS): Article
Pages: str. 1061-1069
Volume: ǂVol. ǂ13
Issue: ǂiss. ǂ2
Chronology: Feb. 2022
DOI: 10.1364/BOE.449814
ID: 14519276
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